This subseries contains material related to Mikulski's political campaigns for the Baltimore City Council, U. S. House of Representatives, and U. S. Senate, as well as materials related to her service to Democratic party organizations such as the Democratic National Committee.

This subseries contains correspondence, scheduling materials and meeting notes for Mikulski and her staff, travel records, political planning materials, and administrative files associated with Mikulski's office operations in Washington, DC and state offices. Examples of material that may be found in this subseries include staff manuals, "NAV" folders prepared to brief Mikulski for events and meetings, staff memos, form letters, and constituent correspondence.

This subseries contains legislative materials related to committee work, drafts of bills, and floor activity.

This subseries contains legislative materials related to committee work, drafts of bills, and floor activity.